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A method for calculating nuclear medicine ionisation chamber (NMIC) calibration settings with a Monte Carlo model is presented and validated against physical measurements. This work provides Monte Carlo calculated calibration settings for select isotopes with no current manufacturer recommendations and a method by which NMIC manufacturers or standards laboratories can utilise highly detailed specifications to calculate comprehensive lists of calibration settings for general isotopes.
A Monte Carlo model of a Capintec PET series NMIC was developed and used to calculate the chamber response to relevant radioactive decay products over an energy range relevant to nuclear medicine. The photon detection efficiency (PDE) of a high purity germanium (HPGe) detector was modelled and physically validated to facilitate measurements of NMIC calibration settings with HPGe detector spectroscopy. Modelled NMIC response to various isotopes was compared against spectroscopic measurements and NIST validated calibration settstandards laboratories can use more detailed specifications of the chamber geometries to extend the applicability of this method to a wider range of isotopes.
Atrial fibrillation (AF) recurrence is common in the 3-month blanking-period after catheter ablation, during which electrical cardioversion (ECV) is usually performed to restore sinus rhythm. Whether ECV can affect the clinical outcome of post-ablation AF patients is inconsistent, however. We aimed to explore the 1-year effect of ECV on AF recurrence and rehospitalization in patients experienced recurrence within 3-month after AF catheter ablation.
Patients who experienced recurrence within 3-month after AF catheter ablation procedure were enrolled from the China Atrial Fibrillation Registry (China-AF). A 13 Propensity score matching (PSM) method was applying to adjust the confounders between patients who had been treated by ECV or not. Logistic regression models were conducted to evaluate the association of ECV with 1-year AF recurrence and rehospitalization.
In this study, 2961 patients experienced AF recurrence within 3-month after the procedure, and 282 of them underwent successful ECV, 2155 patients did not undergo ECV. One-year AF recurrence rates were 56.4% in ECV group versus 65.4% in non-ECV group (p= .003), and were 55.9% versus 65.9%, respectively, after PSM (adjusted odds ratio [OR] 0.66; 95% confidence interval (CI) 0.49-0.88, p= .005). However, the difference of 1-year rehospitalization rates between two groups were not statistically significant before (ECV group 23.7% vs. non-ECV group 22.3%, p= .595) and after PSM (ECV group 24.4% vs. Selleckchem Androgen Receptor Antagonist non-ECV group 21.6%, adjusted OR1.14; 95% CI 0.81-1.62, p= .451).
Successful ECV was associated with lower rate of one-year recurrence in patients with early recurrent AF after catheter ablation.
Successful ECV was associated with lower rate of one-year recurrence in patients with early recurrent AF after catheter ablation.
To assess the utility of cerebroplacental ratio (CPR) and fetal aortic isthmus (AoI) Doppler in the prediction of perinatal outcome in early fetal growth restriction (FGR).
A prospective observational cohort study of 70 early FGR cases was conducted through serial Doppler examinations and findings of the last examination were correlated with perinatal outcome. Doppler blood flow measurements of AoI included end diastolic velocity (EDV), peak systolic velocity (PSV), pulsatility index (PI), resistance index (RI), and isthmic flow index (IFI).
Significant association of CPR and all Doppler indices of AoI with the overall adverse perinatal outcome was seen. The sensitivity of CPR was moderate (63.64%) but higher than most AoI indices. Most AoI Doppler indices (PI, RI, IFI) had higher specificities (100%). AoI PSV and EDV had higher sensitivities than CPR for the prediction of overall adverse perinatal outcome, with AoI PSV having the highest sensitivity (100%).
CPR shows significant association and moderate sensitivity for prediction of overall adverse perinatal outcome in early FGR; hence recommended in all cases of early FGR. AoI Doppler also appears to have a role in assessment and decision making in FGR in view of high sensitivity and high specificity of AoI indices in the prediction of perinatal outcome. However, larger studies are required to confirm its utility in the management of early FGR.
CPR shows significant association and moderate sensitivity for prediction of overall adverse perinatal outcome in early FGR; hence recommended in all cases of early FGR. AoI Doppler also appears to have a role in assessment and decision making in FGR in view of high sensitivity and high specificity of AoI indices in the prediction of perinatal outcome. However, larger studies are required to confirm its utility in the management of early FGR.Rewarding someone who defends the victim of an unjust aggression and punishing someone who chose not to defend her may be very important acts of reciprocation in social life. This study investigates whether 21-month-olds have some expectations concerning such punishing and rewarding actions. Infants were shown simple puppet shows and were tested using the violation-of-expectation paradigm. In Experiment 1, we found that infants looked longer when they saw a bystander puppet punishing the puppet who defended the victim rather than the puppet who did not defend her. This pattern of looking times was reversed when the punishing action was replaced with a rewarding action (Experiment 2). These findings reveal early-emerging expectations about punitive and reward motivations in third-party contexts, and provide some support for theoretical claims about the hardwiring of the human mind for cooperation and prosociality.
Pregnancy period is important for all women. The aim of this study was to evaluate mental status, antenatal depression, attachment, and anxiety in pregnant women with fetal complications.
Mothers who had been diagnosed with fetal complications during pregnancy were interviewed after the delivery of their babies.
The results showed that anxiety and depression scores were significantly higher in the mothers who had received psychiatric support treatment. Maternal attachment scores were found low, depression scores were found high in mothers of children with congenital anomalies.
According to the results of the study, a maternal attachment was low and depression was high in mothers with congenital anomalies.
Possible psychological problems after birth can be prevented by psychotherapeutic nursing interventions during pregnancy to pregnant women who have babies with fetal anomalies.
Possible psychological problems after birth can be prevented by psychotherapeutic nursing interventions during pregnancy to pregnant women who have babies with fetal anomalies.