Phenolic ingredients isolated from Senna tora pals along with their neuroprotective effects versus glutamateinduced oxidative anxiety inside HT22 and also R28 tissues

The mean bacterial colony count increased with time (P < 0.0001). Hand rub use, cleaning of OPD table surfaces with disinfectant, and more number of strokes with cleaning cloth resulted in decrease in colony count of bacteria isolated.
High bacterial contamination of frequently touched OPD table surfaces with variety of potential pathogens like Staphylococcus, Acinetobacter, Pseudomonas, Klebsiella, and E. coli was detected. Hand hygiene among health-care workers and regular and frequent cleaning and disinfection of OPD table surfaces are highly recommended to prevent cross-transmission.
High bacterial contamination of frequently touched OPD table surfaces with variety of potential pathogens like Staphylococcus, Acinetobacter, Pseudomonas, Klebsiella, and E. coli was detected. Hand hygiene among health-care workers and regular and frequent cleaning and disinfection of OPD table surfaces are highly recommended to prevent cross-transmission.
Soil-transmitted helminth (STH) infections have adverse physical and mental effect, especially in preschool (3-6 years) and school-age children (6-14 years). They are associated with socio-behavioral factors of poverty and poor personal and community hygiene.
To determine the prevalence, intensity, and the type of helminths infection harbored by the school age children (6-14 years) and to examine the relationship between STH infection and their potential risk factors and associated variables.
This cross-sectional study was conducted from January to December 2016 among 250 school age children residing in an urban resettlement colony of East Delhi. Data were collected using a semistructured interview schedule. Stool sample was tested using the Kato Katz technique. Data were analyzed in SPSS software version 16, and multivariable regression analysis was done to calculate the odds of various risk factors.
The prevalence of STH was found to be 54.8%, and majority (85.3%) of Ascaris and all Trichuris infections were of light intensity. Multivariable logistic regression analysis confirmed that children having poor handwashing behavior in school, irregular handwashing before eating, having pica, and lack of de-worming had higher odds of having STH infection.
The prevalence of STH in the study area is substantially high, and the findings suggest that besides mass de-worming strategy, behavior change, and improvement in hygiene are required to control STH.
The prevalence of STH in the study area is substantially high, and the findings suggest that besides mass de-worming strategy, behavior change, and improvement in hygiene are required to control STH.
Opioid abuse affects not only user's health but also productivity, security, and health-care costs. Better understanding about the risk factors of opioid use is in need in Myanmar as the country has heavy burdens of opioid abuse.
The present study aimed to identify the determinants of opioid use among adult males in Kachin State, Myanmar.
This case-control study was conducted in Myitkyina city of Kachin State in August 2019. PROTAC tubulin-Degrader-1 Microtubule Associated inhibitor The ratio of case and control was 13, of which there were 109 opioid users and 327 controls who never used illicit drugs. Inclusion criteria for the participants were males of 18 years' old or above. Cases were recruited with the help of a nongovernmental organization, whereas controls were randomly selected from household registration of local government. Data were collected using face-to-face structured questionnaire interview. Multivariable logistic regressions were used to identify the determinants.
The factors associated with opioids use among males in Kachin state had peers who used opioids (adjusted odds ratio [AOR] = 21.67, 95% confident interval [CI] 10.41-45.09), smoking cigarette or cheroot (AOR = 7.5, 95% CI 4.03-13.94), aged 25 years or older (AOR = 3.46, 95% CI 1.73-6.95), and were non-Kachin ethnic (AOR = 2.52, 95% CI 1.36-4.64).
The study indicated that peers had the strongest influence on opioid use, followed by smoking habits as well as age and ethnicity. Effective prevention programs are essential for vulnerable groups.
The study indicated that peers had the strongest influence on opioid use, followed by smoking habits as well as age and ethnicity. Effective prevention programs are essential for vulnerable groups.
Pancreatic fluid collections in early phase of illness <4 weeks after onset of acute pancreatitis (AP) are usually treated with percutaneous drainage (PCD). There is a paucity of data comparing early (<4 weeks) endoscopic transluminal drainage (ETD) with PCD in patients with symptomatic pancreatic necrosis (PN). The objective of this study is to compare the safety and efficacy of early ETD with PCD in patients with symptomatic PN.
Retrospective analysis of database of patients with symptomatic PN treated early (<4 weeks of onset of AP) with either ETD (encapsulated wall on EUS) or PCD.
Twenty-three patients (19 M; mean age 36.1 years) were treated with ETD and 41 patients (29 M; mean age 39.6 years) were treated with PCD, respectively. ETD and PCD were done 24.2 ± 2.3 and 24.2 ± 2.0 days after onset of AP, respectively (P = 0.84). In the ETD group, 35% of patients were treated with self-expanding metallic stents and 48% of patients required direct endoscopic necrosectomy. In the PCD group, 74% of patients were treated with multiple catheters and 91% of patients with either saline or streptokinase irrigation. As compared to the ETD group, patients in the PCD group took longer time for resolution (61.9 ± 22.9 days vs. 30.9 ± 5.6 days; P < 0.00001), increased need for surgery (30% vs. 4%; P = 0.01), and frequency of formation of external pancreatic fistula (EPF) (22% vs. nil; P = 0.02).
ETD of PN in early phase of illness is associated with a shorter duration for resolution and infrequent need of salvage surgery compared to PCD. EPF formation is a significant adverse event with PCD.
ETD of PN in early phase of illness is associated with a shorter duration for resolution and infrequent need of salvage surgery compared to PCD. EPF formation is a significant adverse event with PCD.