MicroRNA single profiles involving solution exosomes produced from kids with nonalcoholic oily liver

Background Climate change is one of the most critical threats to our society. The purpose of this cross-sectional study was to describe the content of the most viewed climate change videos on YouTube. Methods The term "climate change" was used to search on YouTube to garner a sample of the 100most widely-viewed videos. Videos in a language other than English, or considered irrelevant, were excluded. Using a fact sheet from National Aeronautics and Space Administration, content categories were created and successively coded. Results The mean number of views for the 100 videos evaluated was 231,140.2 views (SD=718, 399.5) and the mean length was 12.1 minutes (SD= 24.1). Most videos were uploaded by a news source (77.0%), included a belief that climate change is happening (77.0%), and mentioned the impact of climate change on the environment (71.0%). Only one-third of the videos mentioned how to prevent climate change (33.0%). More than half focused on a specific environment and, of those, 47.2% specifically focused on cities. Compared to videos that did not focus on a specific environment, the videos with an environmental focus were more often intended for adults (87.3% vs. 53.3%, P≤0.001). Conclusion This study highlights the need for climate change YouTube videos intended for youth. Targeting youth may lead to engagement of younger generations in climate change discourse and inspire climate action. Further research is needed to determine the effectiveness of YouTube as a platform for educational videos on climate change.Background In the United States, only about 15% of individuals meet daily fruit intake recommendations of 2 cups per day and only 10% meet the vegetable intake recommendations of3 cups per day. African American women are a high-risk group. In this study, a fourth-generation multi-theory model (MTM) of health behavior change was used to design and evaluate a SistersAdding Fruits and Vegetables for Optimal Results (SAVOR) intervention for AA women. Methods The study utilized a randomized controlled trial (RCT) with measurements taken at pretest, posttest (after the three-week intervention) and follow-up (at the end of eight weeks).SAVOR (n=26) was compared to an equivalent knowledge-based intervention (n=28). Process evaluation was done for program fidelity and satisfaction. A validated 38-item self-reported questionnaire was used to measure changes in MTM constructs and past 24-hour consumption of fruits and vegetables. Results The SAVOR intervention resulted in improvement of mean consumption of fruits and vegetables in the experimental group from pre-test (2.78) to posttest (4.77) to recommended levels at follow-up (5.04) while in the comparison group they remained at around 3 (P less then 0.0001)Statistically significant changes (P less then 0.05) were noted for all MTM constructs except for participatory dialogue. Conclusion The SAVOR intervention was found to be efficacious and established the robustness of MTM. SAVOR can be replicated for future effectiveness trials.Background This study examines the global media framing of coronavirus disease 2019(COVID-19) to understand the dominant frames and how choice of words compares in the media. Periods of health crisis such as the outbreak of coronavirus pandemic add to the enormous burden of the media in keeping people constantly informed. Extant literature suggests that when a message is released through the media, what matters most is not what is said but how it is said. As such, the media could either mitigate or accentuate the crisis depending on the major frames adopted for the coverage. Methods The study utilises content analysis. Data were sourced from LexisNexis database and two websites that yielded 6145 items used for the analysis. Nine predetermined frames were used for the coding. Results Human Interest and fear/scaremongering frames dominated the global media coverage of the pandemic. We align our finding with the constructionist frame perspective which assumes that the media as information processor creates 'interpretative packages' in order to both reflect and add to the 'issue culture' because frames that paradigmatically dominate event coverage also dominate audience response. The language of the coverage of COVID-19 combines gloom, hope, precaution and frustration at varied proportions. Conclusion We conclude that global media coverage of COVID-19 was high, but the framing lacks coherence and sufficient self-efficacy and this can be associated with media's obsession for breaking news. The preponderance of these frames not only shapes public perception and attitudes towards the pandemic but also risks causing more problems for those with existing health conditions due to fear or panic attack.Background The Personal Wellbeing Index-Adults (PWI-A) is the most widely used instrumentfor measuring subjective-quality of life (QoL). The current study seeks to investigate the constructvalidity and reliability of the Arabic version of the PWI-A on adults with bilateral hearingimpairment by comparing the single-factor solution with the two-factor solution. Selleck Cytarabine Methods A cross-sectional study was conducted at the Audio-Vestibular Medicine Unit of Alexandria University from July-2017 to January-2018. A total of 205 adults were interviewed tomeasure the subjective-QoL using the PWI-A instrument. Internal consistency was determinedusing both Cronbach's alpha and composite reliability (CR). Validity was assessed by constructvalidity, including ordinal regression, ordinal exploratory factor analysis (OEFA), and ordinalconfirmatory factor analysis (OCFA). Results The first four items of the PWI-A which are satisfaction with living standard, health,achievements, and relationships were the most important indicators of subjective-wellbeing(Part r2 0.0547, 0.0324, 0.0361, and 0.0225, respectively). OEFA suggested that the two-factormodel contributes better than the single-factor model. OCFA validated this suggested solution;(two-factor RMSEA=0.084 (90% CI=0.01-0.14); CFI=0.964; AIC=52.64; single-factor RMSEA=0.119 (90% CI=0.07-0.17); CFI=0.922; AIC=62.77). Good internal consistency wasalso presented (two-factor Cronbach's alpha=0.719, 0.693; single-factor Cronbach's alpha =0.750). Conclusion The Arabic version of the PWI-A is a multidimensional scale that consists of twodimensions the first is related to subjective-QoL, and the second is related to satisfaction withthe community. Thus, it is recommended to use the short version of the PWI-A with only fouritems to measure subjective-QoL, as it achieved sufficient reliability and construct validity.